Female Infertility
HEALTH APPLICATIONS
It is the situation of couples not being able to get pregnant despite not using protection for a period of 1 year.
Approximately half of the reasons are attributed to the man, the remaining half are attributed to the woman and are considered as unexplained factors. Questioning the vulva, vagina, uterus, tubes and ovaries that make up the female genital system, as well as the neuroendocrinological system that provides regular function in these anatomical structures, will provide important and detailed information about the cause of infertility.
Menarche age, cycle order, presence of dysmenorrhea should be questioned. Menstruation order and last menstrual date information can be evaluated as a rough indicator of the function of the hormonal system that creates menstruation. Dysmenorrhea (painful menstruation) and dyspareunia (painful sexual intercourse) anamnesis can be a warning for endometriosis.
Past operations, past pelvic infections, childhood diseases, familial diseases, and allergic structure should be noted. A detailed anamnesis should be taken in terms of thyroid disorders, pelvic or abdominal pain, breast milk discharge, and hair growth, and any ovulation disorders that may be related to this should also be investigated.
Family history, consanguineous marriage, presence of hereditary diseases, birth defects, and mental retardation are points that should be known before the couple's treatment.
The age of the woman is a very important factor in the definition and treatment of infertility. It is one of the important factors that affects the success of the treatment, usually in parallel with the duration of infertility. The decreasing ovarian reserve and the decrease in the response of the ovaries to drugs in parallel with the increase in age in women negatively affect the success of the treatment. The germ cell pool in the ovary decreases with age.
While there are approximately 1 million oocytes in the ovaries of a newborn girl, this number decreases to 300 thousand during puberty. As menopause approaches, this pool gradually decreases, and the FSH level increases in parallel. The decrease in the number of eggs due to age also causes deterioration in quality.
The aneuploidy rate may be high in eggs formed when using ovulation-stimulating drugs. The risk of chromosomal disorders has also been proven in genetic studies conducted during in vitro fertilization treatment. The chance of pregnancy through egg donation is one of the options for older women.
In addition to routine examination during infertility examination, a cervical passage test should also be performed. In this way, possible negativities during treatment are prevented.
Determining the woman's ovarian reserve is extremely important in terms of directly affecting the treatment to be selected and its success.
The simplest method for determining ovarian reserve is the basal hormone profile and USG examination performed on the 2nd or 3rd day of menstruation. In addition, advanced laboratory tests can be planned.
Endocrine tests: Basal FSH, LH, inhibin-B, AMH.
Thyroid panel and prolactin measurement are also required.
Ultrasonographically: Ovarian volume measurement, antral follicle count.
Routine blood biochemistry, hemogram, hepatitis panel, TORCH group antibodies must be checked before IVF treatment.
Approximately half of the reasons are attributed to the man, the remaining half are attributed to the woman and are considered as unexplained factors. Questioning the vulva, vagina, uterus, tubes and ovaries that make up the female genital system, as well as the neuroendocrinological system that provides regular function in these anatomical structures, will provide important and detailed information about the cause of infertility.
Menarche age, cycle order, presence of dysmenorrhea should be questioned. Menstruation order and last menstrual date information can be evaluated as a rough indicator of the function of the hormonal system that creates menstruation. Dysmenorrhea (painful menstruation) and dyspareunia (painful sexual intercourse) anamnesis can be a warning for endometriosis.
Past operations, past pelvic infections, childhood diseases, familial diseases, and allergic structure should be noted. A detailed anamnesis should be taken in terms of thyroid disorders, pelvic or abdominal pain, breast milk discharge, and hair growth, and any ovulation disorders that may be related to this should also be investigated.
Family history, consanguineous marriage, presence of hereditary diseases, birth defects, and mental retardation are points that should be known before the couple's treatment.
The age of the woman is a very important factor in the definition and treatment of infertility. It is one of the important factors that affects the success of the treatment, usually in parallel with the duration of infertility. The decreasing ovarian reserve and the decrease in the response of the ovaries to drugs in parallel with the increase in age in women negatively affect the success of the treatment. The germ cell pool in the ovary decreases with age.
While there are approximately 1 million oocytes in the ovaries of a newborn girl, this number decreases to 300 thousand during puberty. As menopause approaches, this pool gradually decreases, and the FSH level increases in parallel. The decrease in the number of eggs due to age also causes deterioration in quality.
The aneuploidy rate may be high in eggs formed when using ovulation-stimulating drugs. The risk of chromosomal disorders has also been proven in genetic studies conducted during in vitro fertilization treatment. The chance of pregnancy through egg donation is one of the options for older women.
In addition to routine examination during infertility examination, a cervical passage test should also be performed. In this way, possible negativities during treatment are prevented.
Determining the woman's ovarian reserve is extremely important in terms of directly affecting the treatment to be selected and its success.
The simplest method for determining ovarian reserve is the basal hormone profile and USG examination performed on the 2nd or 3rd day of menstruation. In addition, advanced laboratory tests can be planned.
Endocrine tests: Basal FSH, LH, inhibin-B, AMH.
Thyroid panel and prolactin measurement are also required.
Ultrasonographically: Ovarian volume measurement, antral follicle count.
Routine blood biochemistry, hemogram, hepatitis panel, TORCH group antibodies must be checked before IVF treatment.